Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988379 | 0.92 | KDM4E (0.50) | KDM4EYTHDC1L3MBTL1GLAHTT | |
| SCHEMBL7991565 | 0.89 | TSHR (0.49) | KDM4EYTHDC1L3MBTL1GLAHTT | |
| SCHEMBL7987961 | 0.88 | MAPT (0.47) | YTHDC1ADRA1DMAPTTP53ALDH1A1 | |
| SCHEMBL7985670 | 0.87 | CDK9 (0.42) | KDM4EYTHDC1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7992368 | 0.85 | TP53 (0.47) | YTHDC1ADRA1DMAPTTP53RXFP1 | |
| SCHEMBL7986281 | 0.85 | KMT2A (0.39) | KDM4EYTHDC1MAPTFGFR1FGFR4 | |
| SCHEMBL7974040 | 0.84 | KDM4E (0.51) | KDM4EYTHDC1ADRA1DALDH1A1 | |
| SCHEMBL7973987 | 0.83 | FGFR1 (0.45) | HTTSMN1; SMN2MAPTFGFR1FGFR4 | |
| SCHEMBL7987598 | 0.83 | RIOK2 (0.41) | KDM4EYTHDC1L3MBTL1SMN1; SMN2FGFR1 | |
| SCHEMBL7988641 | 0.82 | KMT2A (0.44) | KDM4ESMN1; SMN2MAPTFGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |