Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991814 | 0.89 | HSP90AA1 (0.44) | ALDH1A1HTTMAPK10LMNAMAPK1 | |
| SCHEMBL7992368 | 0.85 | TP53 (0.47) | MEN1KMT2A | |
| SCHEMBL7986400 | 0.83 | YTHDC1 (0.47) | ALDH1A1HTTMAPK10LMNASMN1; SMN2 | |
| SCHEMBL7973987 | 0.83 | FGFR1 (0.45) | HTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7987598 | 0.83 | RIOK2 (0.41) | ALDH1A1MAPK10SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL7991565 | 0.82 | TSHR (0.49) | ALDH1A1HTTCYP1A2CYP3A4LMNA | |
| SCHEMBL7987961 | 0.81 | MAPT (0.47) | ALDH1A1CYP1A2CYP3A4LMNAKMT2A | |
| SCHEMBL7985495 | 0.81 | CYP11B1 (0.39) | CYP1A2CYP3A4LMNASMN1; SMN2MEN1 | |
| SCHEMBL7985670 | 0.80 | CDK9 (0.42) | ALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL7974162 | 0.80 | KDM4E (0.52) | ALDH1A1HTTSMN1; SMN2L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |