Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992520 | 0.89 | POLB (0.47) | NPC1RAB9ASRCBCHEKDM4E | |
| SCHEMBL7988029 | 0.84 | IDO1 (0.47) | NPC1RAB9ABCHESMN1; SMN2GAA | |
| SCHEMBL7984492 | 0.84 | ADORA2A (0.53) | AURKAAURKBKDM4EALDH1A1 | |
| SCHEMBL7974040 | 0.83 | KDM4E (0.51) | NPC1RAB9AKDM4EALDH1A1NTRK1 | |
| SCHEMBL7974581 | 0.82 | LMNA (0.51) | NPC1RAB9AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL7989385 | 0.82 | PPARG (0.47) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7975241 | 0.82 | GAA (0.50) | NPC1RAB9ASMN1; SMN2NTRK1GAA | |
| SCHEMBL7985375 | 0.82 | KDM4E (0.47) | RAB9AAURKAAURKBKDM4ESMN1; SMN2 | |
| SCHEMBL7991521 | 0.81 | ADORA3 (0.47) | NPC1RAB9AAURKAAURKBKDM4E | |
| SCHEMBL7985506 | 0.80 | GAA (0.48) | BCHEKDM4ESMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |