Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985416 | 0.89 | LMNA (0.50) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL7974581 | 0.86 | LMNA (0.51) | PPARGTSHRLMNAALDH1A1HPGD | |
| SCHEMBL7974040 | 0.84 | KDM4E (0.51) | TSHRKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL7988029 | 0.84 | IDO1 (0.47) | TSHRLMNARXFP1NPC1RAB9A | |
| SCHEMBL7975241 | 0.83 | GAA (0.50) | TSHRLMNARXFP1NPC1RAB9A | |
| SCHEMBL7984492 | 0.83 | ADORA2A (0.53) | KDM4EALDH1A1 | |
| SCHEMBL7985708 | 0.82 | NPC1 (0.49) | TSHRKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL7991817 | 0.81 | KDM4E (0.51) | KDM4ELMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL7984751 | 0.81 | NTRK1 (0.46) | PPARGKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL7973841 | 0.78 | RAB9A (0.47) | TSHRLMNAALDH1A1RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |