Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987443 | 0.87 | GAA (0.37) | GAAHPGDSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7985521 | 0.83 | ALDH1A1 (0.41) | GAAHPGDSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7975252 | 0.82 | HPGD (0.45) | GAAHPGDSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7987782 | 0.82 | NPC1 (0.44) | GAAHPGDSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7992335 | 0.79 | HPGD (0.44) | GAAHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7973934 | 0.76 | CYP11B1 (0.45) | GAAHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7984468 | 0.76 | ABCC8 (0.46) | HPGDSMN1; SMN2ALDH1A1LMNANR1I2 | |
| SCHEMBL7985471 | 0.76 | HPGD (0.43) | GAAHPGDSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7984378 | 0.75 | CYP11B1 (0.42) | GAAHPGDSMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL7988129 | 0.75 | MET (0.44) | GAAHPGDSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |