Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975241 | 0.83 | GAA (0.50) | LMNAADORA3ADORA2ANPC1RAB9A | |
| SCHEMBL7985682 | 0.82 | GAA (0.46) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7985506 | 0.81 | GAA (0.48) | ADORA3SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL7988350 | 0.80 | GAA (0.51) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7988029 | 0.80 | IDO1 (0.47) | LMNAADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7992520 | 0.80 | POLB (0.47) | ADORA3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7985255 | 0.79 | ALDH1A1 (0.51) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7991521 | 0.79 | ADORA3 (0.47) | ADORA3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7991565 | 0.78 | TSHR (0.49) | LMNASMN1; SMN2KMT2AMAPK1ALDH1A1 | |
| SCHEMBL7992192 | 0.78 | HSD17B13 (0.46) | SMN1; SMN2MEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |