Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985033 | 0.91 | NLRP3 (0.46) | MEN1KMT2APOLBKDM4EOPRK1 | |
| SCHEMBL7975241 | 0.88 | GAA (0.50) | HSD17B13GAAPKMTSHRPOLB | |
| SCHEMBL7974265 | 0.86 | MCHR1 (0.47) | HSD17B13MEN1KMT2AGAAPOLB | |
| SCHEMBL7988029 | 0.84 | IDO1 (0.47) | HSD17B13GAAPKMTSHRPOLB | |
| SCHEMBL7985682 | 0.84 | GAA (0.46) | HSD17B13MEN1KMT2AGAAPKM | |
| SCHEMBL7974318 | 0.84 | HSD17B13 (0.43) | HSD17B13GAAPKMTSHRP2RY14 | |
| SCHEMBL7984492 | 0.83 | ADORA2A (0.53) | KDM4ECDK2YTHDC1 | |
| SCHEMBL7985255 | 0.83 | ALDH1A1 (0.51) | MEN1KMT2AGAAPKMTSHR | |
| SCHEMBL7973996 | 0.83 | POLB (0.49) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL7974040 | 0.83 | KDM4E (0.51) | HSD17B13GAAPKMTSHRP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |