Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971749 | 0.89 | KDM4E (0.35) | SLC5A1TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7947164 | 0.78 | PLA2G2A (0.37) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL7982206 | 0.78 | POLB (0.36) | ALDH1A1POLB | |
| SCHEMBL7938360 | 0.77 | POLB (0.36) | L3MBTL1ALDH1A1POLBSLC6A9 | |
| SCHEMBL7945107 | 0.77 | POLB (0.36) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL7948016 | 0.77 | POLB (0.38) | L3MBTL1KDM4EALDH1A1POLBSLC6A9 | |
| SCHEMBL7969219 | 0.77 | KMT2A (0.34) | TDP1L3MBTL1POLB | |
| SCHEMBL7946077 | 0.76 | POLB (0.35) | L3MBTL1ALDH1A1POLBSLC6A9 | |
| SCHEMBL7969073 | 0.75 | MTNR1B (0.35) | KDM4EALDH1A1POLB | |
| SCHEMBL7947094 | 0.75 | POLB (0.37) | KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |