Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.32 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989308 | 0.89 | SLC5A1 (0.34) | KDM4EALDH1A1POLBSLC5A1TDP1 | |
| SCHEMBL7980536 | 0.85 | PTGDR2 (0.35) | POLBPTGDR2SLC6A9 | |
| SCHEMBL7986076 | 0.80 | HDAC1 (0.36) | ALDH1A1PTGDR2EPHX1EPHX2KCNH2 | |
| SCHEMBL7947164 | 0.80 | PLA2G2A (0.37) | ALDH1A1POLBL3MBTL1PTGDR2EPHX2 | |
| SCHEMBL7982206 | 0.79 | POLB (0.36) | ALDH1A1POLBEPHX2 | |
| SCHEMBL7938360 | 0.79 | POLB (0.36) | ALDH1A1POLBL3MBTL1PTGDR2EPHX2 | |
| SCHEMBL7948016 | 0.78 | POLB (0.38) | KDM4EALDH1A1POLBL3MBTL1EPHX2 | |
| SCHEMBL7945107 | 0.78 | POLB (0.36) | ALDH1A1POLBL3MBTL1PTGDR2EPHX2 | |
| SCHEMBL7946077 | 0.78 | POLB (0.35) | ALDH1A1POLBL3MBTL1PTGDR2EPHX2 | |
| SCHEMBL7946743 | 0.77 | MITF (0.45) | KDM4EALDH1A1POLBL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |