Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 5/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997188 | 0.89 | MMP3 (0.40) | L3MBTL1NPC1ATMMMP3KMT2A | |
| SCHEMBL7993470 | 0.89 | MMP3 (0.47) | L3MBTL1NPC1MMP3DHODHKMT2A | |
| SCHEMBL7991480 | 0.84 | MMP3 (0.50) | L3MBTL1NPC1ATMMMP3DHODH | |
| SCHEMBL7997116 | 0.82 | MMP3 (0.69) | L3MBTL1NPC1MMP3TDP1CTSD | |
| SCHEMBL7979043 | 0.78 | MMP3 (0.65) | L3MBTL1NPC1ATMMMP3MAPT | |
| SCHEMBL7993523 | 0.72 | MMP3 (0.70) | L3MBTL1NPC1MMP3DHODHKMT2A | |
| SCHEMBL5503391 | 0.71 | NCEH1 (0.59) | L3MBTL1NPC1KMT2AMEN1CTSD | |
| SCHEMBL10345453 | 0.69 | MAPK1 (0.55) | L3MBTL1NPC1KMT2AMEN1PTGS2 | |
| SCHEMBL10345794 | 0.69 | SMN1; SMN2 (0.58) | L3MBTL1NPC1KMT2AMEN1TSHR | |
| SCHEMBL7979052 | 0.69 | TP53 (0.39) | L3MBTL1NPC1MMP3KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |