Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MRE11 | P49959 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993470 | 0.90 | MMP3 (0.47) | MMP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL7994042 | 0.89 | L3MBTL1 (0.50) | MMP3L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7979052 | 0.80 | TP53 (0.39) | MMP3L3MBTL1TP53SMN1; SMN2KMT2A | |
| SCHEMBL7979043 | 0.75 | MMP3 (0.65) | MMP3L3MBTL1HPGDNPC1ATM | |
| SCHEMBL7993523 | 0.73 | MMP3 (0.70) | MMP3L3MBTL1TP53SMN1; SMN2MEN1 | |
| SCHEMBL7991480 | 0.72 | MMP3 (0.50) | MMP3L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7997116 | 0.72 | MMP3 (0.69) | MMP3L3MBTL1SMN1; SMN2HPGDTDP1 | |
| SCHEMBL28398723 | 0.70 | NPC1 (0.57) | L3MBTL1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL7392898 | 0.68 | TDP1 (0.54) | L3MBTL1HPGDKMT2ATDP1NPC1 | |
| SCHEMBL28396741 | 0.68 | ALDH1A1 (0.55) | L3MBTL1MEN1KMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |