Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997188 | 0.90 | MMP3 (0.40) | MMP3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7994042 | 0.89 | L3MBTL1 (0.50) | MMP3DHODHNPSR1KMT2AMEN1 | |
| SCHEMBL7993523 | 0.83 | MMP3 (0.70) | MMP3ALOX5DHODHALDH1A1NPSR1 | |
| SCHEMBL7979043 | 0.75 | MMP3 (0.65) | MMP3ALDH1A1NPC1L3MBTL1MAPT | |
| SCHEMBL7991480 | 0.72 | MMP3 (0.50) | MMP3DHODHALDH1A1KMT2AMEN1 | |
| SCHEMBL7979052 | 0.70 | TP53 (0.39) | MMP3ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL7997116 | 0.70 | MMP3 (0.69) | MMP3ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL28398723 | 0.70 | NPC1 (0.57) | ALDH1A1NPSR1KMT2AMEN1NPC1 | |
| SCHEMBL28396741 | 0.68 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7392898 | 0.68 | TDP1 (0.54) | ALOX5ALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |