Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736818 | 0.70 | ACLY (0.39) | ACLYMEN1KMT2AKDM4EAGPAT2 | |
| SCHEMBL5735113 | 0.70 | GAA (0.43) | ACLYKDM4EALDH1A1TP53MAPT | |
| SCHEMBL1599472 | 0.70 | ACLY (0.40) | ACLYMEN1KMT2AMAPTGAA | |
| SCHEMBL7994515 | 0.70 | ACLY (0.41) | ACLYMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7995977 | 0.69 | ACLY (0.39) | ACLYMEN1KMT2ATP53MAPT | |
| SCHEMBL5735580 | 0.69 | ACLY (0.39) | ACLYALDH1A1TP53MAPTHSD17B10 | |
| SCHEMBL7978075 | 0.68 | GAA (0.41) | ACLYMEN1KMT2ATP53MAPT | |
| SCHEMBL7995986 | 0.68 | MAPT (0.43) | KDM4EALDH1A1TP53MAPTHSD17B10 | |
| SCHEMBL6790401 | 0.68 | ACLY (0.39) | ACLYMEN1KMT2ATP53MAPT | |
| SCHEMBL5735804 | 0.67 | ACLY (0.37) | ACLYMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |