Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995089 | 0.86 | HTT (0.54) | HTTMAOAMAOBHTR1AL3MBTL1 | |
| SCHEMBL7998680 | 0.82 | HTT (0.48) | HTTALDH1A1ABCB1SMN1; SMN2LTA4H | |
| SCHEMBL7995327 | 0.80 | HTT (0.46) | HTTALDH1A1KMT2AMEN1HTR1A | |
| SCHEMBL7998683 | 0.79 | HTT (0.53) | HTTMAOAMAOBABCB1HTR1A | |
| SCHEMBL7981094 | 0.76 | HTT (0.45) | HTTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL23637666 | 0.72 | L3MBTL1 (0.56) | HTTALDH1A1KMT2AMEN1KDM1A | |
| SCHEMBL7995324 | 0.72 | HTT (0.55) | HTTMAOAMAOBL3MBTL1SMN1; SMN2 | |
| SCHEMBL7995311 | 0.72 | CALM1 (0.44) | HTTMAOBL3MBTL1KDM4E | |
| SCHEMBL31276017 | 0.70 | L3MBTL1 (0.66) | ALDH1A1MAOAMAOBL3MBTL1CYP3A4 | |
| SCHEMBL64435 | 0.68 | L3MBTL1 (0.68) | ALDH1A1MAOAMAOBABCB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009129-A2 | 1H-PIRIDO[3, 4-B]INDOL-1-ONE DERIVATIVES | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |