Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645324 | 0.85 | LTA4H (0.58) | HTR7LTA4HCYP3A4MAPK14RAB9A | |
| SCHEMBL7143886 | 0.84 | RAB9A (0.51) | HTR7LTA4HCYP3A4MAPK14RAB9A | |
| Hydrochloric Acid SCHEMBL5253545 | 0.84 | LTA4H (0.56) | HTR7LTA4HCYP3A4MAPK14RAB9A | |
| SCHEMBL1993655 | 0.79 | L3MBTL1 (0.58) | LTA4HCYP3A4RAB9ANAMPTNPC1 | |
| SCHEMBL6280945 | 0.79 | ALDH1A1 (0.56) | RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL6282350 | 0.76 | THRA (0.61) | MAPT | |
| SCHEMBL17088991 | 0.76 | LMNA (0.65) | CYP3A4NPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL2512740 | 0.76 | RAB9A (0.64) | CYP3A4MAPK14RAB9ANAMPTNPC1 | |
| SCHEMBL6283043 | 0.75 | KMT2A (0.57) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6283084 | 0.75 | RAB9A (0.56) | RAB9ANAMPTNPC1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001057018-A1 | AZAAZULENE INHIBITORS OF P38 MAP KINASE AND TNF-ALPHA | ABBOTT LABORATORIES (US) | 2001-08-09 | — | — | WO | disclosed |