Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996807 | 0.90 | DHPS (0.53) | EDNRADHPS | |
| SCHEMBL7997001 | 0.89 | EDNRA (0.51) | EDNRA | |
| SCHEMBL7997033 | 0.84 | EDNRB (0.49) | EDNRADHPS | |
| SCHEMBL7993553 | 0.84 | DHPS (0.50) | EDNRADHPS | |
| SCHEMBL7993994 | 0.81 | EDNRB (0.56) | EDNRADHPS | |
| SCHEMBL7979093 | 0.81 | ALDH1A1 (0.47) | EDNRADHPS | |
| SCHEMBL7979130 | 0.80 | GPR84 (0.39) | EDNRADHPS | |
| SCHEMBL7993871 | 0.79 | EDNRB (0.56) | EDNRADHPS | |
| SCHEMBL7997032 | 0.79 | EDNRB (0.59) | EDNRADHPS | |
| SCHEMBL7979433 | 0.79 | EDNRB (0.38) | EDNRADHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |