Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979428 | 0.90 | PLK1 (0.42) | EDNRBEDNRAALDH1A1MAPTPLK1 | |
| SCHEMBL7979130 | 0.82 | GPR84 (0.39) | EDNRBEDNRAALDH1A1DHPSMAPT | |
| SCHEMBL7997005 | 0.79 | EDNRA (0.52) | EDNRADHPS | |
| SCHEMBL7996807 | 0.77 | DHPS (0.53) | EDNRBEDNRADHPS | |
| SCHEMBL7979093 | 0.76 | ALDH1A1 (0.47) | EDNRBEDNRAALDH1A1DHPSMAPT | |
| SCHEMBL7993990 | 0.74 | RAB9A (0.44) | EDNRBEDNRAALDH1A1MAPTPOLB | |
| SCHEMBL7991615 | 0.74 | GPR84 (0.42) | EDNRBEDNRAALDH1A1DHPSMAPT | |
| SCHEMBL7997033 | 0.72 | EDNRB (0.49) | EDNRBEDNRAALDH1A1DHPS | |
| SCHEMBL7993553 | 0.72 | DHPS (0.50) | EDNRBEDNRADHPSPOLBIRAK4 | |
| SCHEMBL7979128 | 0.72 | MAPT (0.41) | EDNRBEDNRAALDH1A1MAPTPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |