Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DHPS | P49366 | 10/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979090 | 0.90 | ALDH1A1 (0.42) | ALDH1A1EDNRAEDNRBHPGDMAPT | |
| SCHEMBL7993990 | 0.87 | RAB9A (0.44) | ALDH1A1EDNRAEDNRBHPGDMAPT | |
| SCHEMBL7997005 | 0.81 | EDNRA (0.52) | DHPSEDNRA | |
| SCHEMBL7993983 | 0.79 | PIK3CA (0.42) | ALDH1A1EDNRAEDNRBMAPTPTK2 | |
| SCHEMBL7991472 | 0.79 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL7996807 | 0.78 | DHPS (0.53) | DHPSEDNRAEDNRB | |
| SCHEMBL7979130 | 0.76 | GPR84 (0.39) | ALDH1A1DHPSEDNRAEDNRBHPGD | |
| SCHEMBL7979433 | 0.76 | EDNRB (0.38) | ALDH1A1DHPSEDNRAEDNRBPLK1 | |
| SCHEMBL7991615 | 0.75 | GPR84 (0.42) | ALDH1A1DHPSEDNRAEDNRBMAPT | |
| SCHEMBL7993553 | 0.74 | DHPS (0.50) | DHPSEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |