Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426759 | 0.77 | HTR6 (0.68) | HTR6KDM4EALDH1A1CCR1 | |
| SCHEMBL6740915 | 0.74 | HTR6 (0.48) | HTR6KDM4EALDH1A1CCR1MAPT | |
| SCHEMBL6426403 | 0.74 | HTR6 (0.48) | HTR6KDM4EALDH1A1CCR1MAPT | |
| SCHEMBL30684143 | 0.63 | CA2 (0.56) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL670176 | 0.63 | CA2 (0.56) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL7006323 | 0.63 | CYP1A2 (0.55) | MAPT | |
| SCHEMBL7010984 | 0.61 | SLC6A4 (0.53) | — | |
| SCHEMBL7006099 | 0.61 | SLC6A4 (0.53) | — | |
| SCHEMBL7005001 | 0.61 | HTR1A (0.47) | HTR6KMT2A | |
| SCHEMBL7006270 | 0.61 | HTR1B (0.58) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032660-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR ANTAGONIST ACTIVITY | NPS ALLELIX CORP. (US) | 2001-05-10 | — | — | WO | disclosed |