SCHEMBL7998327

SCHEMBL7998327

Cc1nsc(NC(=O)C(F)c2ccc3nc(CC(C)(C)C)cnc3c2)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.32
FFAR2 O15552 1/20 0.31
BUB1 O43683 1/20 0.31
ABL1 P00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7994515 0.81 ACLY (0.41) MAPK14FFAR2BUB1
SCHEMBL7997945 0.81 SMN1; SMN2 (0.36)
SCHEMBL8001777 0.76 SCN9A (0.33)
SCHEMBL5735580 0.71 ACLY (0.39) FFAR2
SCHEMBL7998323 0.71
SCHEMBL6790401 0.70 ACLY (0.39) MAPK14FFAR2BUB1
SCHEMBL5735982 0.68 MAOA (0.37) FFAR2
SCHEMBL7998418 0.67 MAPT (0.33) ABL1
SCHEMBL7984009 0.64 CACNA1H (0.38)
SCHEMBL5736347 0.63 MAPT (0.44) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001055140-A1 ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed