Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998415 | 0.72 | KDM4E (0.39) | MAPTKDM4EALDH1A1GAARAB9A | |
| SCHEMBL7997967 | 0.70 | KDM4E (0.41) | MAPTKDM4EALDH1A1GAARAB9A | |
| SCHEMBL5736347 | 0.67 | MAPT (0.44) | MAPTALDH1A1KMT2AGRM1GAA | |
| SCHEMBL5734469 | 0.67 | RAB9A (0.43) | MAPTALDH1A1KMT2AGRM5GRM1 | |
| SCHEMBL7998327 | 0.67 | MAPK14 (0.32) | ABL1 | |
| Bromide SCHEMBL8001925 | 0.66 | MAPT (0.42) | MAPTALDH1A1KMT2AGRM1GAA | |
| SCHEMBL5735580 | 0.64 | ACLY (0.39) | MAPTALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7994515 | 0.64 | ACLY (0.41) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL7994622 | 0.63 | FFAR2 (0.32) | ALDH1A1 | |
| SCHEMBL5735982 | 0.63 | MAOA (0.37) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |