Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035205 | 0.76 | HTR6 (0.50) | PKMHTR6LMNAALDH1A1KMT2A | |
| SCHEMBL9713812 | 0.75 | PKM (0.49) | PKMCYP2C19TSHRHTR6LMNA | |
| SCHEMBL27842733 | 0.74 | THRB (0.47) | PKMLMNACYP3A4ALDH1A1NPC1 | |
| Dapsone SCHEMBL1533643 | 0.73 | TSHR (0.73) | PKMCYP2C19TSHRHTR6LMNA | |
| Dapsone SCHEMBL27601804 | 0.73 | TSHR (0.73) | PKMCYP2C19TSHRHTR6LMNA | |
| SCHEMBL8003877 | 0.73 | HTR6 (0.54) | PKMCYP2C19TSHRHTR6LMNA | |
| SCHEMBL927344 | 0.72 | HTR6 (0.58) | PKMCYP2C19TSHRHTR6LMNA | |
| Dapsone SCHEMBL28433097 | 0.70 | TSHR (0.67) | PKMCYP2C19TSHRHTR6LMNA | |
| SCHEMBL1703357 | 0.70 | HTR6 (0.60) | PKMTSHRHTR6LMNAMPO | |
| SCHEMBL17774709 | 0.70 | HTR6 (0.62) | PKMTSHRHTR6LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019403-B1 | HYDROXYALKYL-STARCH DRUG CARRIER | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1985-07-31 | — | — | EP | disclosed |
| EP-0028641-A4 | HYDROXYALKYL STARCH DRUG CARRIER. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1981-09-01 | — | — | EP | disclosed |
| EP-0028641-A1 | HYDROXYALKYL STARCH DRUG CARRIER. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1981-05-20 | — | — | EP | disclosed |
| WO-1980002374-A1 | HYDROXYALKYL STARCH DRUG CARRIER | AMERICAN HOSPITAL SUPPLY CORP (US) | 1980-11-13 | — | — | WO | disclosed |