Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002704 | 0.92 | HTR6 (0.41) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL13622839 | 0.85 | SLC6A4 (0.42) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL13622807 | 0.83 | LMNA (0.33) | ALDH1A1MEN1KMT2ALMNAHTR2A | |
| SCHEMBL13622805 | 0.78 | EPHX2 (0.33) | HRH3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13622809 | 0.78 | KMT2A (0.44) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2090738 | 0.78 | KMT2A (0.44) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13622997 | 0.77 | HRH3 (0.35) | HRH3ALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL13622841 | 0.77 | HTR2A (0.38) | HRH3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2096559 | 0.76 | KMT2A (0.42) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13478900 | 0.73 | ALDH1A1 (0.43) | HRH3L3MBTL3L3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108117-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |