Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.54 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | BMP1 | P13497 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350174 | 0.94 | ALDH1A1 (0.81) | ALDH1A1TAS2R14MEP1BCXCR3PTGES | |
| SCHEMBL7003868 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TP53MEN1KMT2ANPSR1 | |
| SCHEMBL5093686 | 0.88 | ALDH1A1 (0.72) | ALDH1A1TAS2R14LMNAMEP1BCXCR3 | |
| SCHEMBL8002039 | 0.86 | DAGLA (0.76) | DAGLATAS2R14MEP1BCXCR3PTGES | |
| SCHEMBL8008258 | 0.85 | DAGLA (0.61) | ALDH1A1DAGLATAS2R14MEP1BCXCR3 | |
| SCHEMBL5577038 | 0.83 | MEP1B (0.78) | DAGLATAS2R14MEP1BTHRBBMP1 | |
| SCHEMBL22252122 | 0.82 | KEAP1 (0.73) | ALDH1A1TAS2R14LMNACXCR3PTGES | |
| SCHEMBL7000836 | 0.82 | BMP1 (0.69) | ALDH1A1TP53TAS2R14BMP1 | |
| SCHEMBL1169298 | 0.80 | TAS2R14 (0.88) | MEN1KMT2ATAS2R14MEP1BCXCR3 | |
| SCHEMBL15772656 | 0.80 | RORC (0.59) | ALDH1A1DAGLATAS2R14MEP1BCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845987-A4 | C-PROTEINASE INHIBITORS FOR THE TREATMENT OF DISORDERS RELATED TO THE OVERPRODUCTION OF COLLAGEN | FIBROGEN INC (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-0845987-A1 | C-PROTEINASE INHIBITORS FOR THE TREATMENT OF DISORDERS RELATED TO THE OVERPRODUCTION OF COLLAGEN | FIBROGEN, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997005865-A1 | C-PROTEINASE INHIBITORS FOR THE TREATMENT OF DISORDERS RELATED TO THE OVERPRODUCTION OF COLLAGEN | FIBROGEN, INC. (US) | 1997-02-20 | — | — | WO | disclosed |