Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024336 | 0.95 | FFAR1 (0.50) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8020340 | 0.94 | MMP12 (0.48) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8026644 | 0.92 | NOX1 (0.52) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8010235 | 0.92 | MMP12 (0.47) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8026747 | 0.90 | ALOX5 (0.52) | FFAR1MAOBMMP12FFAR4 | |
| SCHEMBL8024296 | 0.89 | NOX1 (0.48) | MAOBMMP12MEN1KMT2A | |
| SCHEMBL8021316 | 0.88 | NPC1 (0.49) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8024571 | 0.88 | FFAR1 (0.46) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8021221 | 0.87 | MEN1 (0.48) | FFAR1MAOBMMP12KEAP1FFAR4 | |
| SCHEMBL8024699 | 0.87 | FFAR1 (0.43) | FFAR1MAOBMMP12FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | claimed |
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | disclosed |