Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33773 | 0.86 | TDP1 (0.44) | MEN1LDHABLMKMT2ATDP1 | |
| SCHEMBL4162002 | 0.76 | ALOX15 (0.46) | LDHATDP1ALDH1A1LMNAOR51E2 | |
| SCHEMBL6901765 | 0.76 | TDP1 (0.36) | TDP1ALDH1A1LMNAOR51E2 | |
| Carbimide SCHEMBL7758388 | 0.76 | TDP1 (0.36) | TDP1ALDH1A1LMNAOR51E2 | |
| SCHEMBL370642 | 0.75 | — | — | |
| Acrylamide SCHEMBL1526851 | 0.74 | ALDH1A1 (0.58) | TDP1ALDH1A1LMNAOR51E2 | |
| SCHEMBL10380940 | 0.72 | — | — | |
| SCHEMBL370643 | 0.72 | — | — | |
| SCHEMBL21693817 | 0.72 | ALDH1A1 (0.38) | TDP1ALDH1A1LMNAOR51E2 | |
| SCHEMBL4558368 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034584-A1 | GLYOXALATED POLYACRYLAMIDES AS PAPER STRENGTHENING AGENTS | HERCULES INCORPORATED (US) | 2000-06-15 | — | — | WO | disclosed |