Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324677 | 0.89 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1MAPK1CFDPLG | |
| SCHEMBL8015222 | 0.84 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1MAPK1PAMPOLB | |
| SCHEMBL8682147 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPK1CFDPLG | |
| SCHEMBL503961 | 0.81 | L3MBTL1 (0.77) | L3MBTL1ALDH1A1POLBSMN1; SMN2GLA | |
| SCHEMBL6687005 | 0.80 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1MAPK1PAMTDP1 | |
| SCHEMBL5661211 | 0.79 | TBXAS1 (0.53) | L3MBTL1ALDH1A1MAPK1CFDPLG | |
| SCHEMBL9003138 | 0.79 | HRH1 (0.61) | L3MBTL1ALDH1A1MAPK1KDM4E | |
| SCHEMBL1007508 | 0.78 | CFD (0.68) | L3MBTL1ALDH1A1CFDPLGPLAU | |
| SCHEMBL4576519 | 0.78 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1POLBSMN1; SMN2GLA | |
| SCHEMBL31757965 | 0.78 | CFD (0.68) | L3MBTL1ALDH1A1CFDPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107284-A | Water-soluble derivatives of epipodophyllotoxin, process for their preparation, their use as medicinal products and their intended use in anti-cancer treatments | PIERRE FABRE MEDICAMENT (FR) | 2000-08-22 | — | — | US | disclosed |