Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12862306 | 0.78 | KDM4E (0.33) | — | |
| SCHEMBL25589752 | 0.77 | MEN1 (0.35) | CNR2 | |
| SCHEMBL23987102 | 0.75 | LMNA (0.35) | CNR2 | |
| SCHEMBL25590340 | 0.74 | MEN1 (0.39) | CNR2 | |
| SCHEMBL24530159 | 0.74 | MEN1 (0.39) | CNR2 | |
| SCHEMBL15454836 | 0.74 | CNR2 (0.41) | CNR2 | |
| SCHEMBL23970350 | 0.72 | MEN1 (0.38) | CNR2 | |
| SCHEMBL4716380 | 0.72 | MEN1 (0.41) | — | |
| SCHEMBL23970178 | 0.72 | MEN1 (0.41) | — | |
| SCHEMBL756416 | 0.72 | GRN (0.36) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238100-B1 | PROCESS FOR THE SYNTHESIS OF 3-AMINO-3-CYCLOBUTYLMETHYL-2-HYDROXYPROPIONAMIDE OR SALTS THEREOF | MERCK SHARP & DOHME (US) | 2014-03-26 | — | — | EP | disclosed |
| US-8586765-B2 | Process for the synthesis of 3-amino-3-cyclobuthylmethyl-2-hydroxypropionamide or salts thereof | MERCK SHARP & DOHME CORP. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110034705-A1 | Process For the Synthesis of 3- Amino-3-Cyclobuthylmethyl-2-Hydroxypropionamide or Salts Thereof | SCHERING-PLOUGH CORPORATION (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110034705-A1 | Process For the Synthesis of 3- Amino-3-Cyclobuthylmethyl-2-Hydroxypropionamide or Salts Thereof | SCHERING-PLOUGH CORPORATION (US) | 2011-02-10 | — | — | US | disclosed |
| US-20090312576-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 3-(AMINO)-3-CYCLOBUTYLMETHYL-2-HYDROXY-PROPIONAMIDE OR SALTS THEREOF | SCHERING CORPORATION | 2009-12-17 | — | — | US | disclosed |
| US-20090312576-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 3-(AMINO)-3-CYCLOBUTYLMETHYL-2-HYDROXY-PROPIONAMIDE OR SALTS THEREOF | SCHERING CORPORATION | 2009-12-17 | — | — | US | disclosed |
| US-7595419-B2 | Process and intermediates for the preparation of 3-(amino)-3-cyclobutylmethyl-2-hydroxy-propionamide or salts thereof | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-7595419-B2 | Process and intermediates for the preparation of 3-(amino)-3-cyclobutylmethyl-2-hydroxy-propionamide or salts thereof | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| WO-2009085858-A1 | PROCESS FOR THE SYNTHESIS OF 3-AMINO-3-CYCLOBUTYLMETHYL-2-HYDROXYPROPIONAMIDE OR SALTS THEREOF | SCHERING CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312576-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 3-(AMINO)-3-CYCLOBUTYLMETHYL-2-HYDROXY-PROPIONAMIDE OR SALTS THEREOF | PCCA, IDH3A, ALDH18A1 | CNR2 119/4885 |
| US-20110034705-A1 | Process For the Synthesis of 3- Amino-3-Cyclobuthylmethyl-2-Hydroxypropionamide or Salts Thereof | PAH, DHPS, ACMSD | CNR2 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.