Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033888 | 0.90 | HPGD (0.49) | MTNR1AMTNR1BMAPTTHRBALDH1A1 | |
| SCHEMBL8037878 | 0.88 | MTNR1A (0.55) | MTNR1AMTNR1BPLA2G2AMAPTTHRB | |
| SCHEMBL25136 | 0.85 | MTNR1B (0.60) | MTNR1AMTNR1BPLA2G2AMAPTPSEN1 | |
| SCHEMBL8034000 | 0.83 | LMNA (0.50) | MTNR1AMTNR1BMAPTTHRBALDH1A1 | |
| SCHEMBL5160095 | 0.78 | PLA2G2A (0.52) | MTNR1AMTNR1BPLA2G2AMAPTALDH1A1 | |
| SCHEMBL4757197 | 0.78 | MTNR1B (0.52) | MTNR1AMTNR1BPLA2G2AMAPTTHRB | |
| SCHEMBL8033990 | 0.76 | PLA2G2A (0.67) | PLA2G2APLA2G1B | |
| SCHEMBL6333369 | 0.75 | PLA2G2A (0.65) | PLA2G2APLA2G1B | |
| SCHEMBL6340494 | 0.75 | PLA2G2A (0.65) | PLA2G2APLA2G1B | |
| SCHEMBL5697008 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BPLA2G2APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987250-A1 | INDOLE DICARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |