Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033888 | 0.90 | HPGD (0.49) | MTNR1AMTNR1BMAPTTHRBALDH1A1 | |
| SCHEMBL8023979 | 0.88 | MTNR1A (0.46) | MTNR1AMTNR1BMAPTTHRBALDH1A1 | |
| SCHEMBL8034000 | 0.87 | LMNA (0.50) | MTNR1AMTNR1BMAPTTHRBALDH1A1 | |
| SCHEMBL26473 | 0.78 | MTNR1B (0.67) | MTNR1AMTNR1BMAPTPLA2G2A | |
| SCHEMBL5882106 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTTP53 | |
| SCHEMBL25136 | 0.74 | MTNR1B (0.60) | MTNR1AMTNR1BMAPTKDM4EPLA2G2A | |
| SCHEMBL28039679 | 0.73 | HDAC6 (0.56) | MAPTTHRBALDH1A1GAAPKM | |
| SCHEMBL6775247 | 0.71 | CCR2 (0.65) | MTNR1AMTNR1BMAPTTHRBALDH1A1 | |
| SCHEMBL8502661 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BMAPTALDH1A1GAA | |
| SCHEMBL6771136 | 0.70 | MTNR1B (0.70) | MTNR1AMTNR1BMAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987250-A1 | INDOLE DICARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |