Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009991 | 0.84 | MAPK1 (0.35) | ALDH1A1LMNAMAPK1POLBL3MBTL1 | |
| SCHEMBL8022618 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1LMNAKMT2AMAPK1 | |
| SCHEMBL8024286 | 0.71 | ADRA2A (0.54) | LMNA | |
| SCHEMBL1553581 | 0.68 | KMT2A (0.63) | ALDH1A1MEN1LMNAKMT2AMAPK1 | |
| SCHEMBL66188 | 0.67 | TSHR (0.70) | ALDH1A1LMNAKMT2AMAPK1POLB | |
| SCHEMBL16835426 | 0.65 | LMNA (0.50) | ALDH1A1MEN1LMNAKMT2AMAPK1 | |
| SCHEMBL13979786 | 0.65 | HTR6 (0.65) | HTR6 | |
| SCHEMBL4169872 | 0.65 | MAPK1 (0.47) | ALDH1A1LMNAMAPK1POLBL3MBTL1 | |
| SCHEMBL5012595 | 0.64 | SMN1; SMN2 (0.59) | ALDH1A1LMNAKMT2AMAPK1HTR6 | |
| SCHEMBL1178903 | 0.64 | PTGS2 (0.53) | ALDH1A1MEN1LMNAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971900-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPY | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042679-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPY | SANOFI-SYNTHELABO (FR) | 1998-10-01 | — | — | WO | disclosed |