Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026070 | 1.00 | FUT7 (0.43) | FUT7CA2TLR8NR1I2KAT8 | |
| SCHEMBL27995540 | 0.86 | KAT8 (0.41) | TLR8KAT8S1PR1S1PR3PPARA | |
| SCHEMBL8026398 | 0.85 | TLR8 (0.40) | TLR8KAT8S1PR1S1PR3PPARA | |
| SCHEMBL8026073 | 0.85 | TLR8 (0.40) | TLR8KAT8S1PR1S1PR3PPARA | |
| SCHEMBL1720960 | 0.83 | SLC2A1 (0.42) | LMNACYP2D6CYP2C19HTTKCNH2 | |
| SCHEMBL383821 | 0.83 | SLC2A1 (0.42) | LMNACYP2D6CYP2C19HTTKCNH2 | |
| SCHEMBL7782536 | 0.83 | SLC2A1 (0.42) | LMNACYP2D6CYP2C19HTTKCNH2 | |
| SCHEMBL7782546 | 0.83 | SLC2A1 (0.42) | LMNACYP2D6CYP2C19HTTKCNH2 | |
| SCHEMBL7781797 | 0.83 | SLC2A1 (0.42) | LMNACYP2D6CYP2C19HTTKCNH2 | |
| SCHEMBL5669839 | 0.83 | SLC2A1 (0.42) | LMNACYP2D6CYP2C19HTTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719851-B1 | Lubricating oil composition | ASAHI DENKA KOGYO KK (JP) | 2000-02-23 | — | — | EP | disclosed |
| US-5627146-A | A MOLYBDENUM DITHIOCARBAMATE, IMPROVED STABILITY AND SOLUBILITY | ASAHI DENKA KOGYO K.K. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0719851-A2 | Lubricating oil composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1996-07-03 | — | — | EP | disclosed |