SCHEMBL8029462

SCHEMBL8029462

Fc1cccc(F)c1P(Cl)c1c(F)cccc1F

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
BCHE P06276 1/20 0.32
NFE2L2 Q16236 3/20 0.32
GAA P10253 1/20 0.31
ALB P02768 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1042764 0.82 CES2 (0.36) ACHECES2CES1TAAR1ALDH1A1
SCHEMBL8035545 0.71 CES2 (0.32) CES2CES1ALDH1A1ERN1
SCHEMBL1039758 0.71 CES2 (0.36) ACHECES2CES1BCHENFE2L2
SCHEMBL19968584 0.71 CES2 (0.36) ACHECES2CES1ALDH1A1BCHE
SCHEMBL30426297 0.69 ACHE (0.38) ACHECES2CES1TAAR1ALDH1A1
SCHEMBL2154282 0.69 ACHE (0.38) ACHECES2CES1TAAR1ALDH1A1
SCHEMBL1041826 0.68 MAPT (0.39) ALDH1A1GAA
SCHEMBL1040594 0.68 CYP2A6 (0.45) ALDH1A1
SCHEMBL1041734 0.68 CA2 (0.40) ALDH1A1
SCHEMBL1041027 0.67 ACHE (0.48) ACHECES2CES1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-09 US disclosed
CN-107548385-B Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-21 CN disclosed
CN-113896607-A Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
CN-107592863-B Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-09-10 CN disclosed
CN-107567355-B Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-06 US disclosed
US-10981156-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-20 US disclosed
US-10919031-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-16 US disclosed
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-29 US disclosed
US-10702861-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-07 US disclosed
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-30 US disclosed
US-10376869-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2019-08-13 US disclosed
US-10357764-B2 Phosphacycle compound and process for production thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-23 US disclosed
US-20190210013-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-11 US disclosed
US-10207262-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-19 US disclosed
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-07 US disclosed
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-15 US disclosed
US-6084133-A REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY KANKYO KAGAKU CENTER CO., LTD. (JP) 2000-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM ACHE 110/4885CES2 994/4885CES1 745/4885
US-10919031-B2 Process for oligomerization OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-10376869-B2 Process for oligomerization OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-10981156-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ACHE 110/4885CES2 994/4885CES1 745/4885
US-10357764-B2 Phosphacycle compound and process for production thereof OXER1, PPIP5K2, IP6K1 ACHE 182/4885CES2 1582/4885CES1 709/4885
US-10207262-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ACHE 110/4885CES2 994/4885CES1 745/4885
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885
US-20190210013-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM ACHE 110/4885CES2 994/4885CES1 745/4885
US-10702861-B2 Process for oligomerization OXER1, NOD1, LIG1 ACHE 307/4885CES2 1949/4885CES1 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.