Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12872368 | 0.82 | TSHR (0.34) | ADORA2AADORA2BTSHR | |
| SCHEMBL13868048 | 0.79 | — | — | |
| SCHEMBL18427027 | 0.79 | — | — | |
| SCHEMBL21719520 | 0.79 | — | — | |
| SCHEMBL12733049 | 0.77 | — | — | |
| SCHEMBL8744682 | 0.76 | KDM4E (0.35) | ADORA2AADORA2BTSHR | |
| SCHEMBL21719768 | 0.76 | — | — | |
| SCHEMBL21719981 | 0.76 | — | — | |
| SCHEMBL12138138 | 0.74 | ADORA2A (0.32) | ADORA2AADORA2B | |
| SCHEMBL12859227 | 0.74 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-9556205-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9556205-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9545105-B2 | 1-(heterocyclic carbonyl) piperidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-17 | — | — | US | disclosed |
| US-9320277-B2 | Fungicide N-cycloalkyl-N-biphenylmethyl-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-20160023987-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-28 | — | — | US | disclosed |
| US-9173399-B2 | Benzocycloalkenes as antifungal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-8927581-B2 | Fungicidal N-(2-pyridylpropyl) carboxamide derivatives and their oxa, aza and thia analogues | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8841332-B2 | Fungicidal N-(2-phenoxyethyl)carboxamide derivatives and their aza, thia and sila analogues | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-06-09 | — | — | US | disclosed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | SINOCHEM CORPORATION | 2011-02-24 | — | — | US | disclosed |
| US-20100144817-A1 | FUNGICIDEL N-CYCLOALKYL-BENZYL-THIOCARBOXAMIDES OR N-CYCLOALKYL-BENZYL-N'-SUBSTITUTED-AMIDINE DERIVATIVES | BAYER SAS (FR) | 2010-06-10 | — | — | US | disclosed |
| US-20100130560-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-THIO CARBOXAMIDE OR 2-PYRIDYL-METHYLENE-N-SUBSTITUTED CARBOXIMIDAMIDE DERIVATIVES | BAYER SAS (FR) | 2010-05-27 | — | — | US | disclosed |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20090326016-A1 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023987-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | CYP51A1, ERG28, CBR1 | ADORA2A 4052/4885ADORA2B 4332/4885TSHR 4193/4885 |
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | ACHE, MGAM, PGLS | ADORA2A 126/4885ADORA2B 590/4885TSHR 2543/4885 |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | ADORA2A 858/4885ADORA2B 1988/4885TSHR 2711/4885 |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CYP4X1, PDXK | ADORA2A 858/4885ADORA2B 1988/4885TSHR 2711/4885 |
| US-20100144817-A1 | FUNGICIDEL N-CYCLOALKYL-BENZYL-THIOCARBOXAMIDES OR N-CYCLOALKYL-BENZYL-N'-SUBSTITUTED-AMIDINE DERIVATIVES | CBR3, NRDC, NAT1 | ADORA2A 956/4885ADORA2B 1926/4885TSHR 809/4885 |
| US-20110136874-A1 | FUNGICIDAL N-(2-PYRIDYLPROPYL) CARBOXAMIDE DERIVATIVES AND THEIR OXA, AZA AND THIA ANALOGUES | PNPO, AZI2, CYP51A1 | ADORA2A 408/4885ADORA2B 1290/4885TSHR 1177/4885 |
| US-20100010048-A1 | Fungicide 2-pyridyl-methylene-carboxamide derivatives | CYP51A1, ME2, ME3 | ADORA2A 2970/4885ADORA2B 3753/4885TSHR 3931/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | ADORA2A 3720/4885ADORA2B 4268/4885TSHR 2995/4885 |
| US-20090326016-A1 | FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES | CBR3, CBR1, CYCS | ADORA2A 2714/4885ADORA2B 3025/4885TSHR 2086/4885 |
| US-20100130560-A1 | FUNGICIDE 2-PYRIDYL-METHYLENE-THIO CARBOXAMIDE OR 2-PYRIDYL-METHYLENE-N-SUBSTITUTED CARBOXIMIDAMIDE DERIVATIVES | CBR3, CBR1, CNPY2 | ADORA2A 1044/4885ADORA2B 2157/4885TSHR 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.