Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044066 | 0.85 | HTT (0.45) | HSD17B10GABRA5GABRB2LMNAHPGD | |
| SCHEMBL8033073 | 0.83 | RAB9A (0.36) | LMNAPOLBHTTNPC1RAB9A | |
| SCHEMBL8044541 | 0.83 | ALOX15 (0.41) | HSD17B10GABRA5GABRB2LMNAHPGD | |
| SCHEMBL8033866 | 0.82 | HSD17B10 (0.40) | HSD17B10GABRA5GABRB2LMNATDP1 | |
| SCHEMBL8042994 | 0.81 | GABRA5 (0.41) | HSD17B10GABRA5GABRB2LMNAHPGD | |
| SCHEMBL8041849 | 0.80 | RAB9A (0.38) | HSD17B10LMNATDP1HPGDPOLB | |
| SCHEMBL8051238 | 0.79 | HSD17B10 (0.42) | HSD17B10GABRA5GABRB2LMNATDP1 | |
| SCHEMBL8032345 | 0.78 | HSD17B10 (0.43) | HSD17B10GABRA5GABRB2LMNAHPGD | |
| SCHEMBL8044409 | 0.77 | ALDH1A1 (0.40) | HSD17B10GABRA5GABRB2LMNATDP1 | |
| SCHEMBL8050622 | 0.77 | MEN1 (0.40) | HSD17B10HPGDPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |