Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 5/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045389 | 0.87 | RXRA (0.40) | RXRARXRBRXRGHCAR2USP7 | |
| SCHEMBL8049983 | 0.85 | RXRA (0.39) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL8037025 | 0.85 | MEN1 (0.37) | MEN1KMT2ASCD | |
| SCHEMBL8033057 | 0.83 | RAB9A (0.44) | RXRARXRBRXRG | |
| SCHEMBL8044846 | 0.83 | RAB9A (0.42) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL8043417 | 0.81 | HDAC6 (0.36) | RXRARXRBRXRG | |
| SCHEMBL8044469 | 0.81 | MAPK8 (0.46) | MEN1KMT2A | |
| SCHEMBL8034005 | 0.81 | MEN1 (0.34) | MEN1KMT2ASCDRECQL | |
| SCHEMBL8043447 | 0.80 | RXRA (0.43) | RXRARXRBRXRGHCAR2USP7 | |
| SCHEMBL8043545 | 0.77 | RXRA (0.40) | RXRARXRBRXRGHCAR2USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |