Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037062 | 0.91 | SMPD1 (0.51) | HPGDLMNAALDH1A1MAPK1HTT | |
| SCHEMBL8039245 | 0.89 | MRGPRX4 (0.49) | HPGDLMNAALDH1A1MAPK1HTT | |
| SCHEMBL8039263 | 0.89 | SMN1; SMN2 (0.54) | HPGDLMNAALDH1A1MAPK1HTT | |
| SCHEMBL8023140 | 0.87 | MTNR1B (0.49) | HPGDLMNAALDH1A1MAPK1HTT | |
| SCHEMBL8035471 | 0.86 | CTSV (0.54) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL8025476 | 0.84 | SMPD1 (0.47) | HPGDSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL8039259 | 0.84 | LMNA (0.51) | HPGDLMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL8025540 | 0.83 | SMN1; SMN2 (0.48) | HPGDLMNAALDH1A1MAPK1HTT | |
| SCHEMBL8035613 | 0.83 | S1PR1 (0.54) | HPGDALDH1A1SGMS2TP53MAPT | |
| SCHEMBL8025544 | 0.83 | ALDH1A1 (0.49) | HPGDLMNAALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |