Sugi Predict

Sugi Predict / Compounds / SCHEMBL80368

SCHEMBL80368

SCHEMBL80368

FC(F)(F)C1(c2ccccc2)N=N1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 1/20 0.43
▸ MAOB P27338 7/20 0.40
▸ MAOA P21397 4/20 0.40
▸ ADRA2A P08913 1/20 0.40
▸ GABRB3 P28472 5/20 0.38
▸ GABRA1 P14867 4/20 0.38
▸ GABRG2 P18507 4/20 0.38
▸ ALDH1A1 P00352 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ GABRB2 P47870 2/20 0.35
▸ OPRM1 P35372 1/20 0.33
▸ OPRL1 P41146 1/20 0.33
▸ PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5275595 0.93 MAOB (0.39) KIF11MAOBMAOAADRA2AGABRB3
SCHEMBL22587363 0.83 ADRA2A (0.49) KIF11MAOBMAOAADRA2AGABRB3
SCHEMBL31751941 0.82 KIF11 (0.50) KIF11ALDH1A1TSHRPDK2
SCHEMBL30970983 0.80 KIF11 (0.61) KIF11ADRA2AGABRB3GABRA1GABRG2
SCHEMBL20336329 0.80 KIF11 (0.61) KIF11ADRA2AGABRB3GABRA1GABRG2
SCHEMBL23860299 0.76 KIF11 (0.45) KIF11ADRA2AGABRB3GABRA1GABRG2
SCHEMBL20261725 0.76 KIF11 (0.45) KIF11ADRA2AGABRB3GABRA1GABRG2
SCHEMBL22587365 0.76 KIF11 (0.45) KIF11MAOBMAOAADRA2AGABRB3
SCHEMBL14655026 0.76 KIF11 (0.49) KIF11ADRA2AGABRB3GABRA1GABRG2
SCHEMBL13619662 0.76 KIF11 (0.45) KIF11MAOBMAOAADRA2AGABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731603-A1 LOW TEMPERATURE REACTIVE ARYL AZIDES SuSoS AG (CH) 2026-04-29 — — EP claimed
WO-2025095666-A1 NOVEL OXOCYANINE-BASED COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 포항공과대학교 산학협력단 2025-05-08 — — WO claimed
WO-2024261308-A1 LOW TEMPERATURE REACTIVE ARYL AZIDES SUSOS AG (CH) 2024-12-26 — — WO claimed
US-20210231677-A1 TRACELESS IMMOBILIZATION OF ANALYTES FOR SAMDI MASS SPECTROMETRY NORTHWESTERN UNIVERSITY 2021-07-29 — — US claimed
WO-2019237019-A9 TRACELESS IMMOBILIZATION OF ANALYTES FOR SAMDI MASS SPECTROMETRY NORTHWESTERN UNIVERSITY (US) 2020-06-11 — — WO claimed
US-10551388-B2 Method of determining a protein in a sample RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) 2020-02-04 — — US claimed
EP-2877857-B1 METHOD OF DETERMINING A PROTEIN IN A SAMPLE UNIV BONN RHEINISCHE FRIEDRICH WILHELMS (DE) 2019-03-13 — — EP claimed
US-10005936-B2 Photoactive bioadhesive compositions NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2018-06-26 — — US claimed
US-20180143201-A1 METHOD OF DETERMINING A PROTEIN IN A SAMPLE CARIS MPI, INC. 2018-05-24 — — US claimed
US-9910045-B2 Method of determining a protein in a sample RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT BONN (DE) 2018-03-06 — — US claimed
WO-2015031265-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SURMODICS, INC. (US) 2015-03-05 — — WO claimed
WO-2014016368-A1 METHOD OF DETERMINING A PROTEIN IN A SAMPLE RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) 2014-01-30 — — WO claimed
EP-2690441-A1 Method of determining a protein in a sample Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2014-01-29 — — EP claimed
US-20100226938-A1 Cellular and viral inactivation HEALTH AND HUMAN SERVICES, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF 2010-09-09 — — US claimed
US-20090297558-A1 Inactivated Influenza Virus Compositions DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2009-12-03 — — US claimed
WO-2008054481-A2 IMPROVED INACTIVATED INFLUENZA VIRUS COMPOSITIONS GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2008-05-08 — — WO claimed
CN-1954066-A Cellular and viral inactivation US GOVERNMENT (US) 2007-04-25 — — CN claimed
US-7084285-B2 Photoaffinity-labeled sphingomyelin analogs and processes thereof DAISO CO., LTD. (JP) 2006-08-01 — — US claimed
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue BRITISH COLUMBIA, UNIVERSITY OF, THE (CA) 2003-01-16 — — US claimed
WO-2002076453-A1 METHODS AND COMPOSITIONS FOR PHOTO-CROSS LINKING PHOTOACTIVE COMPOUNDS TO TARGET TISSUE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-10-03 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10005936-B2 Photoactive bioadhesive compositions L1CAM, CDH1, PCNA KIF11 2656/4885MAOB 1751/4885MAOA 949/4885
US-20090297558-A1 Inactivated Influenza Virus Compositions ITPA, IDO1, IDE KIF11 1689/4885MAOB 839/4885MAOA 401/4885
US-20100226938-A1 Cellular and viral inactivation TP53, IFNG, POLI KIF11 2536/4885MAOB 2407/4885MAOA 2292/4885
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue LCP1, PPOX, TYR KIF11 4114/4885MAOB 474/4885MAOA 704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.