Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037438 | 0.84 | S1PR1 (0.45) | S1PR1KDM4EGAAAPPADRB2 | |
| SCHEMBL8039185 | 0.82 | PYGL (0.49) | KDM4EGAAPYGLMAPTMAPK1 | |
| SCHEMBL8040252 | 0.81 | ALDH1A1 (0.41) | S1PR1KDM4EGAAMAPT | |
| SCHEMBL8037415 | 0.81 | S1PR1 (0.41) | S1PR1GAAAPPADRB2GPR183 | |
| SCHEMBL8041411 | 0.81 | S1PR1 (0.43) | S1PR1KDM4EAPPMAPT | |
| SCHEMBL8025554 | 0.81 | MTNR1A (0.42) | S1PR1KDM4EAPPAURKB | |
| SCHEMBL8040180 | 0.81 | S1PR1 (0.58) | S1PR1KDM4EPYGLADRB2GPR183 | |
| SCHEMBL8028301 | 0.81 | APP (0.39) | S1PR1KDM4EGAAAPPADRB2 | |
| SCHEMBL8037435 | 0.80 | PDE10A (0.41) | S1PR1APP | |
| SCHEMBL8037394 | 0.80 | POLB (0.46) | S1PR1KDM4EGAAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |