Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040845 | 0.80 | CA12 (0.46) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL3633054 | 0.77 | CA12 (0.61) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL29551674 | 0.77 | CA12 (0.61) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL321832 | 0.76 | ABL1 (0.62) | CA12CA1CA2CA9NR1H4 | |
| SCHEMBL7707561 | 0.76 | MMP3 (0.44) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL4541662 | 0.75 | CA12 (0.59) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL29551646 | 0.75 | CA12 (0.59) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL7047570 | 0.74 | PPARG (0.52) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL8040747 | 0.74 | ACHE (0.42) | PPARGPPARACA1CA2CA9 | |
| SCHEMBL6800358 | 0.73 | LTA4H (0.39) | PPARGCA1CA2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438638-B1 | Process for producing norcamphane dicarbonitriles | MITSUI CHEMICALS INC (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5087722-A | Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0438638-A1 | Process for producing norcamphane dicarbonitriles | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-31 | — | — | EP | disclosed |