Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038284 | 0.87 | ALDH1A1 (0.49) | PPARAPTPN1SMN1; SMN2TSPO | |
| SCHEMBL8041238 | 0.85 | LTA4H (0.51) | PPARAPTPN1TSHR | |
| SCHEMBL6408806 | 0.85 | ALOX5 (0.50) | PPARAPTPN1TSPOPPARG | |
| SCHEMBL8041220 | 0.84 | MTNR1A (0.41) | PTPN1SMN1; SMN2 | |
| SCHEMBL8039703 | 0.83 | LTA4H (0.53) | PTPN1TSHR | |
| SCHEMBL8044308 | 0.83 | PTPN1 (0.45) | PTPN1SMN1; SMN2NSD2CASP3CASP7 | |
| SCHEMBL8044214 | 0.82 | SMN1; SMN2 (0.39) | PTPN1SMN1; SMN2NSD2CASP3CASP7 | |
| SCHEMBL8027754 | 0.81 | ALDH1A1 (0.41) | PPARAPTPN1SMN1; SMN2NSD2CASP3 | |
| SCHEMBL6407413 | 0.80 | MEN1 (0.52) | PTPN1NSD2CASP3CASP7CASP9 | |
| SCHEMBL8027747 | 0.80 | ALDH1A1 (0.47) | PTPN1TSPOMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |