Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ACACA | Q13085 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039723 | 0.88 | PNLIP (0.47) | ALDH1A1PNLIPKMT2AACACBACACA | |
| SCHEMBL8044308 | 0.86 | PTPN1 (0.45) | ALDH1A1KMT2ATSPOMEN1TSHR | |
| SCHEMBL8041220 | 0.84 | MTNR1A (0.41) | ACACBACACAMCL1BCL2L1MDM2 | |
| SCHEMBL8038284 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSPOPTPN1 | |
| SCHEMBL6407413 | 0.82 | MEN1 (0.52) | ALDH1A1KMT2AMEN1TSHRLMNA | |
| SCHEMBL8041238 | 0.81 | LTA4H (0.51) | TSHRTP53PTPN1 | |
| SCHEMBL6408806 | 0.81 | ALOX5 (0.50) | ALDH1A1ACACBMCL1TSPOPTPN1 | |
| SCHEMBL8044214 | 0.80 | SMN1; SMN2 (0.39) | KMT2AACACBACACATSPOMEN1 | |
| SCHEMBL6401909 | 0.80 | PTPN1 (0.51) | KMT2AMCL1BCL2L1MEN1TSHR | |
| SCHEMBL8034169 | 0.79 | PTPN1 (0.50) | ALDH1A1KMT2AMEN1TSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |