Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039703 | 0.98 | LTA4H (0.53) | LTA4HPTPN11PLK1TP53TSHR | |
| SCHEMBL8038284 | 0.93 | ALDH1A1 (0.49) | LTA4HPTPN1PPARA | |
| SCHEMBL8037870 | 0.88 | LTA4H (0.46) | LTA4HPLK1TSHR | |
| SCHEMBL8027754 | 0.86 | ALDH1A1 (0.41) | LTA4HTSHRPTPN1PPARA | |
| SCHEMBL8037882 | 0.86 | LTA4H (0.48) | LTA4HPTPN11PLK1TP53TSHR | |
| SCHEMBL6408806 | 0.86 | ALOX5 (0.50) | PTPN1PPARA | |
| SCHEMBL8044214 | 0.85 | SMN1; SMN2 (0.39) | TSHRPTPN1PTPRA | |
| SCHEMBL8041138 | 0.85 | PPARA (0.39) | TSHRPTPN1PPARA | |
| SCHEMBL8041220 | 0.85 | MTNR1A (0.41) | TP53PTPN1 | |
| SCHEMBL8044308 | 0.84 | PTPN1 (0.45) | LTA4HTSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |