Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044175 | 0.89 | TSPO (0.43) | MTNR1AMTNR1BPOLBSMN1; SMN2ACACB | |
| SCHEMBL8044214 | 0.89 | SMN1; SMN2 (0.39) | MTNR1AMTNR1BPOLBSMN1; SMN2ACACB | |
| SCHEMBL8038284 | 0.87 | ALDH1A1 (0.49) | SMN1; SMN2MAPTPTPN1 | |
| SCHEMBL8041238 | 0.85 | LTA4H (0.51) | PTPN1TP53 | |
| SCHEMBL6408806 | 0.85 | ALOX5 (0.50) | MCL1ACACBPTPN1 | |
| SCHEMBL8027747 | 0.84 | ALDH1A1 (0.47) | MCL1BCL2L1ACACBACACAMDM2 | |
| SCHEMBL8039703 | 0.83 | LTA4H (0.53) | MAPTPTPN1TP53 | |
| SCHEMBL8044308 | 0.83 | PTPN1 (0.45) | SMN1; SMN2HPGDPTPN1 | |
| SCHEMBL8027754 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2PTPN1 | |
| SCHEMBL6407413 | 0.80 | MEN1 (0.52) | POLBHPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |