Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039724 | 0.89 | TSPO (0.41) | TSPOACACBACACAMTNR1AMTNR1B | |
| SCHEMBL8041220 | 0.89 | MTNR1A (0.41) | ACACBACACAMTNR1AMTNR1BPOLB | |
| SCHEMBL8037899 | 0.86 | MAPT (0.51) | TSPOMTNR1AMTNR1BTSHRKMT2A | |
| SCHEMBL8037870 | 0.85 | LTA4H (0.46) | TSPOTSHRKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL8039723 | 0.85 | PNLIP (0.47) | TSPOACACBACACATSHRGAA | |
| SCHEMBL6405714 | 0.84 | ALOX5 (0.47) | TSPOACACBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6403207 | 0.83 | TSPO (0.45) | TSPOTSHRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8037882 | 0.83 | LTA4H (0.48) | TSPOTSHRSMN1; SMN2TP53MAPT | |
| SCHEMBL8041192 | 0.82 | TSPO (0.41) | TSPOTSHRGAAKMT2ASMN1; SMN2 | |
| SCHEMBL6340722 | 0.78 | MAOB (0.44) | TSPOACACBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |