Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037882 | 0.98 | LTA4H (0.48) | LTA4HPLA2G2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8037899 | 0.92 | MAPT (0.51) | LTA4HCYP1A2CYP2C19SMN1; SMN2TSPO | |
| SCHEMBL8041238 | 0.88 | LTA4H (0.51) | LTA4HTSHRPLK1 | |
| SCHEMBL8041192 | 0.87 | TSPO (0.41) | LTA4HSMN1; SMN2TSPOMAPTRAB9A | |
| SCHEMBL8039703 | 0.86 | LTA4H (0.53) | LTA4HMAPTL3MBTL1TSHRLMNA | |
| SCHEMBL8039724 | 0.86 | TSPO (0.41) | SMN1; SMN2TSPOMAPTRAB9ATSHR | |
| SCHEMBL8044175 | 0.85 | TSPO (0.43) | SMN1; SMN2TSPOMAPTTSHRTDP1 | |
| SCHEMBL6405714 | 0.85 | ALOX5 (0.47) | SMN1; SMN2TSPORAB9A | |
| SCHEMBL6403207 | 0.84 | TSPO (0.45) | LTA4HSMN1; SMN2TSPOL3MBTL1TSHR | |
| SCHEMBL8039723 | 0.81 | PNLIP (0.47) | TSPOMAPTTSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |