Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240777 | 0.85 | SLC18A3 (0.39) | MEN1KMT2AMGLLSLC18A3 | |
| SCHEMBL4355747 | 0.81 | EPHX2 (0.36) | MGLLEPHX2EPHX1 | |
| SCHEMBL16499606 | 0.80 | MAOA (0.33) | SIGMAR1 | |
| SCHEMBL8041595 | 0.79 | RAB9A (0.36) | MGLLSLC18A3 | |
| SCHEMBL6432221 | 0.75 | MGLL (0.34) | MEN1KMT2AMGLL | |
| SCHEMBL8602242 | 0.73 | SMN1; SMN2 (0.38) | MEN1KMT2AMGLL | |
| SCHEMBL23294742 | 0.72 | ALDH1A1 (0.35) | MGLL | |
| SCHEMBL16684620 | 0.72 | SLC6A3 (0.34) | MGLLSLC18A3 | |
| SCHEMBL5016154 | 0.72 | ALDH1A1 (0.37) | MEN1KMT2AMGLLEPHX2 | |
| SCHEMBL20535408 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630560-B2 | Containing aryl groups subsituted with halo and alcohol groups; used as absorbers of hydrogen bond basic analytes such as organophosphonate esters (nerve agents and precursors) and nitro-substituted compounds (explosives). | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2003-10-07 | — | — | US | disclosed |
| US-20020026026-A1 | Linear and branched chemoselective siloxane polymers and methods for use in analytical and purification applications | NAVY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2002-02-28 | — | — | US | disclosed |
| WO-2002008314-A1 | LINEAR CHEMOSELECTIVE POLYSILOXANES FOR CHEMICAL SENSOR APPLICATIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2002-01-31 | — | — | WO | disclosed |