SCHEMBL4355747

SCHEMBL4355747

c1ccc(C[SiH](Cc2ccccc2)C2CCCCO2)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.36
ALDH1A1 P00352 3/20 0.35
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
RAB9A P51151 2/20 0.34
MGLL Q99685 1/20 0.34
GAA P10253 1/20 0.33
EPHX1 P07099 1/20 0.33
HPGD P15428 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16499606 0.85 MAOA (0.33)
SCHEMBL16684620 0.83 SLC6A3 (0.34) ALDH1A1SMN1; SMN2RAB9AMGLLHPGD
SCHEMBL5016154 0.83 ALDH1A1 (0.37) EPHX2ALDH1A1SMN1; SMN2RAB9AMGLL
SCHEMBL23294742 0.83 ALDH1A1 (0.35) ALDH1A1POLBSMN1; SMN2RAB9AMGLL
SCHEMBL28774732 0.82 SLC6A3 (0.33) ALDH1A1SMN1; SMN2RAB9AMGLLHPGD
SCHEMBL7249559 0.81 MEN1 (0.40) EPHX2MGLLEPHX1
SCHEMBL305087 0.81 G6PC1 (0.34) ALDH1A1SMN1; SMN2RAB9AMGLL
SCHEMBL16684674 0.80 SLC6A3 (0.35) EPHX2ALDH1A1SMN1; SMN2RAB9AHPGD
SCHEMBL11766465 0.80 TACR1 (0.34) ALDH1A1POLBSMN1; SMN2RAB9AMGLL
SCHEMBL8041595 0.74 RAB9A (0.36) SMN1; SMN2RAB9AMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2133394-B1 METHOD FOR PRODUCING A FLAT-SURFACE INSULATING FILM-COATED SUBSTRATE AND FLAT-SURFACE INSULATING FILM-COATED SUBSTRATE NIPPON STEEL & SUMIKIN MAT CO (JP) 2014-12-31 EP disclosed
EP-2133394-A1 COATING SOLUTION FOR SURFACE FLAT INSULATING FORMATION, SURFACE FLAT INSULATING FILM COVERING BASE MATERIAL, AND PROCESS FOR PRODUCING SURFACE FLAT INSULATING FILM COVERING BASE MATERIAL Nippon Steel Materials Co., Ltd. (JP) 2009-12-16 EP disclosed
EP-0240254-A2 Polymerization catalyst, production and use EXXON CHEMICAL PATENTS INC. (US) 1987-10-07 EP disclosed