Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043000 | 0.77 | DCUN1D1 (0.42) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL8047366 | 0.70 | TAAR1 (0.40) | KDM4EMEN1KMT2AIDO1CYP3A4 | |
| SCHEMBL9135463 | 0.70 | ALDH1A1 (0.52) | KMOALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL8049878 | 0.68 | ALOX5 (0.39) | ALDH1A1KDM4EHPGD | |
| SCHEMBL8046545 | 0.67 | ALOX15 (0.33) | ALDH1A1 | |
| SCHEMBL28204863 | 0.64 | KMO (0.35) | KMOALDH1A1ALPLKDM4EMEN1 | |
| SCHEMBL29294900 | 0.63 | TRPV4 (0.43) | KMOALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL2030502 | 0.62 | KMO (0.36) | KMOALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9057929 | 0.62 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1USP2DHFR | |
| SCHEMBL8046050 | 0.62 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |