Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046050 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL8042855 | 0.70 | ALDH1A1 (0.45) | ALOX15ALDH1A1MAPK1 | |
| SCHEMBL11013516 | 0.70 | ALOX15 (0.52) | ALOX15HSP90AA1TLR9S100A4ALDH1A1 | |
| SCHEMBL8046152 | 0.68 | CHRNB4 (0.31) | — | |
| SCHEMBL8049878 | 0.68 | ALOX5 (0.39) | HSP90AA1ALDH1A1 | |
| Water SCHEMBL28487363 | 0.67 | ALOX15 (0.50) | ALOX15HSP90AA1TLR9S100A4ALDH1A1 | |
| SCHEMBL8044636 | 0.63 | — | — | |
| SCHEMBL8048510 | 0.63 | MMP12 (0.33) | — | |
| SCHEMBL8044837 | 0.63 | — | — | |
| SCHEMBL10479111 | 0.62 | ALOX15 (0.44) | ALOX15HSP90AA1TLR9S100A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |